Customization and Preparation Define DHMRI Genomics Services

The Genomics team at the David H. Murdock Research Institute (DHMRI), located on the NC Research Campus in Kannapolis, NC, knows that scientists looking for genomics expertise more often need customized solutions than off-the-shelf kits. 

The Genomics laboratory offers support starting with the study design through sample processing and data analysis.

“Most people don’t realize that DHMRI’s genomics scientists are very responsive to our collaborators while simultaneously doing an unbelievably good job at maintaining very high throughput and very high quality data,” said Simon  Gregory, PhD, DHMRI scientific advisor and associate professor in the section of Medical Genetics, Department of Medicine at Duke University.

All in the Preparation

The DHMRI Genomics Laboratory features two Illumina HiSeq 2500 sequencing platforms, but “our advantage,” Bostrom said, “is the different types of library preparations we can do.”

The Genomics team performs genomic DNA and RNA library preparation as well as mate pair sequencing, which provides long-range information and methylation status profiling. In partnership with 10X Genomics, long-range bar coding and single cell transcriptome library preparation is available. As a preferred provider of Cambridge Epigentix, the DHMRI Genomics team is helping to develop technologies for epigenetics studies.

The Genomics Team also develops and validates QPCR assays, specialized extraction protocols and methods to work with “nontraditional” samples and species.  

Learn more about the capabilities and services of the DHMRI’s Genomics Laboratory.

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