Bioinformatics

We are equipped with a dedicated bioinformatics team that employs a broad range of analytical tools to analyze the large data sets that are generated in the laboratories. Bioinformatics facilitates a collaborative environment using technology and business disciplines for acquiring, managing, integrating, optimizing, analyzing, inferring and referencing disparate data for our Genomic, Proteomic, Metabolomic, and In Vitro sciences laboratories.

At the union of science and technology, the bioinformatics group touches every area of scientific research within our Institute.

Services by laboratory:

Genomics

  • Advanced Sequencing QC Analysis
  • Reference mapping/alignments
  • Variant Calling (SNV/SNP)
  • Structural Variation Detection (indels, inversions, CNV, etc.)
  • De novo genomic assembly, finishing, and annotation
  • Metagenomic assembly
  • Transcriptomics
    • Novel splicing sites, exon, and transcript discovery
    • RNASeq and Differential Expression Analysis (microarray data as well)
    • Small RNA analysis
    • De novo assembly
    • RNA secondary structure prediction
  • Pathway analysis
  • Targeted Resequencing Analysis
  • Bis-DNA and methylated DNA sequencing analysis
  • ChIP-Seq analysis
  • Phylogenetics
  • BLAST/database querying and analysis
  • Genome Wide Association Studies (GWAS)

Proteomics

  • Expression profiling
  • Pathway analysis
  • BLAST/database querying and analysis
  • Pattern discovery
  • Motif discovery
  • Signal peptide discovery
  • Secondary structural determination and prediction
  • Clustering

Metabolomics

  • Pathway analysis
  • Data annotation
  • Multivariate analysis

 

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