Protein Ligand Binding Assays

In our NMR laboratory, we run NMR Saturation Transfer Difference (STD) experiments to determine protein/ligand binding or corresponding binding constants.  HSQC experiments determine binding location and involved residues on a given protein.  A SampleJet 480-autosampler  for the rapid creation of large screening libraries. Complexes or large multimer proteins are verified with mass spectral data collected in our in-house proteomics facility

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